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What is CBD
Cannabidiol—CBD—is a cannabis compound that has significant medical benefits, but does not make people feel “stoned” and can actually counteract the psychoactivity of THC.
The fact that CBD-rich cannabis is non-psychoactive or less psychoactive than THC-dominant strains makes it an appealing option for patients looking for relief from inflammation, pain, anxiety, psychosis, seizures, spasms, and other conditions without disconcerting feelings of lethargy or dysphoria.
Scientific and clinical research—much of it sponsored by the US government—underscores CBD’s potential as a treatment for a wide range of conditions, including arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, depression, antibiotic-resistant infections, epilepsy, and other neurological disorders. CBD has demonstrable neuroprotective and neurogenic effects, and its anti-cancer properties are currently being investigated at several academic research centers in the United States and elsewhere. Further evidence suggests that CBD is safe even at high doses.
Vetting and How it works?
What is CBD?
Advanced Video Series on CBD
Cannabinoid and Terpenoid Reference
Terpenes synergistic with CBD
To search by dosage threads only
Crohn's / UC / Digestive
Epilepsy / Seizure
Arthritis / AS
Headaches / Migraines
Frequently Asked Questions
How does CBD work with (X) Medication?
- CBD has been shown in large quantities to interact with your CYP450, essentially “deactivating” it. This obviously being not good as it can cause adverse reactions with medications, especially anxiolytics. (Heighten/weaken strength, or activation of side effects like nausea, etc)
Does CBD Oil make you nauseous?
- People sometimes feel this way due to the carrier oil used, make sure you eat before taking it- You may be sensitive to the coconut oil or carrier oil.
What's Full-spectrum vs Isolate?
- Full spectrum means the product contains THC and other cannabinoids, not just CBD. Isolate means it's solely CBD, or the listed cannabinoid. (CBN, CBG, etc)
Will CBD make me positive on drug tests?
- See above. If Full-Spectrum it's fully possible to test positive. If it's isolate, it shouldn't.
CBD with Keppra? Depakote? Diazepam? Clobazam? (Insert anticonvulsant here)
- Advise caution when mixing any anticonvulsant with CBD as it can pose risks as mentioned earlier with CYP450- Talk to your Neurologist/Epileptologist before committing. (Or ask Dr. Krishna!)
How does Omega-3 work with CBD?
- Essentially it's said that Omega-3 deficiencies do have a correlation with low CB1 response, especially being that omega-3 deficiencies are a fairly common occurrence with the American diet. Low Omega-3 can lead to seasonal affect disorder- “Using mice, the study found that a deficiency in Omega-3 caused presynaptic CB1 receptors to uncouple from their effector G proteins, essentially disabling them. This dietary-induced impairment of CB1 function adversely affected emotional behavior.”, So essentially when Omega 3 is inplace its holding the CB receptors, preventing de-coupling. So with Omega-3 usage with CBD you are ensuring the CB receptors are not degraded, or decoupled, thus ensuring maximum potential benefit. There's a good study about this and MDD here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC533861/
How do I know if CBD is working?
- Typically CBD is shown as 'working' per symptomatic relief. It will not cure your ailments, merely treat symptoms- nausea, pain, anxiety, depression, etc. Compare yourself prior to taking it, and after. You should have relief from what you're looking to address- if not, try a higher dosage.
Am I doing this right? I don't feel the effect I thought I was going to feel?
- Due to CB1/CB2 cluster sizes, everyone experiences CBD slightly differently. If you're expecting something like a THC high, or even alcohol inebriation- you're not thinking about it right. Ideally, you will feel almost perfectly normal, just without the given symptom you're looking to address. E.g. Pain > No Pain.
“What's a good starting dose? I see studies using 300+ mg doses. I can't afford that every day!”
- A starting dose would be 10-20mg daily. It is thought that CBD somewhat builds up in your body over the first week or so you are taking it, so the first few days you may not notice much of an effect. Once established, 30mg is considered a full daily dose for average people. Some with extreme pain or other ailments may up the dose to 50mg or more. If you need much more than 50-70mg daily then CBD may not be the best cost effective option for you.
It seems that studies like the one you mention use large doses because, in all honesty, the effects of CBD with a daily dose are difficult to establish and empirically record. They use such large doses so that it exaggerates the effects for the study to actually see them.
A commonly expressed view of the effects of CBD is simply that it makes you feel normal, it only really takes away symptoms and pain, instead of causing you to feel something. That is inherently difficult to observe in a scientific method, because it is subjective for each person. Hence why they use such a large dose.
What are some high CBD strains?
Can I vape this tincture?
- Probably not advised. Very few tinctures can actually be vaped.
What are some hemp based CBD companies I should avoid?
While we haven't tested any of these products ourselves to verify, user reports indicate that the following statements may be true so we recommend being careful for personal safety. Caveat emptor:
(avoid) Omega Labs
Avoid Diamond CBD THEY ARE REPORTED TO HAVE SYNETHIC DANGEROUS DRUGS IN THEIR PRODUCTS
(avoid) Just Chill
(avoid) Medical Marijuana Inc.
“CHRONIC CBD” products have been reported to be synthetic (i.e. K2/Spice).
Will CBD make me pop positive on a drug test?
Reasons why it might
Is there THC in CBD products?
What is the typical CBD dosage used?
What is the effect of combining THC with CBD?
Where can I find dispensaries that offer high CBD strains in my area?
Please do not assume that anyone here is a medical professional. Anything you see here in support of CBD is purely anecdotal, as CBD has yet to be regulated by the FDA.
Contamination from metals and pesticides are common. There are currently no companies fully endorsed by the FDA. If you are considering purchasing a CBD product have it tested for yourself if possible.
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